KLK15 Antibody
| Code | Size | Price |
|---|
| PSI-58-018-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Kallikrein-15, 3421-, ACO protease, KLK15
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Kallikreins are a subgroup of serine proteases having
diverse physiological functions. Growing evidence suggests that
many kallikreins are implicated in carcinogenesis and some have
potential as novel cancer and other disease biomarkers. This gene
is one of the fifteen kallikrein subfamily members located in a
cluster on chromosome 19. In prostate cancer, this gene has
increased expression, which indicates its possible use as a
diagnostic or prognostic marker for prostate cancer. The gene
contains multiple polyadenylation sites and alternative splicing
results in multiple transcript variants encoding distinct isoforms.
Background References:
- Rabien, A., et al. Int. J. Cancer 127(10):2386-2394(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
- Gallagher, D.J., et al. Clin. Cancer Res. 16(10):2819-2832(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KLK15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-106 amino acids from the Central region of human KLK15.
NCBI Gene ID #:
55554
NCBI Official Name:
Kallikrein-15
NCBI Official Symbol:
KLK15
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
Q9H2R5
Protein GI Number:
18202940
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
Q9H2R5
User NOte:
Optimal dilutions for each application to be determined by the researcher.