ADAM19 Antibody
| Code | Size | Price |
|---|
| PSI-64-129-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Disintegrin and metalloproteinase domain-containing protein 19, ADAM 19, 3424-, Meltrin-beta, Metalloprotease and disintegrin dendritic antigen marker, MADDAM, ADAM19, MLTNB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Background:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction.
Background References:
- Hancock, D.B., et al. Nat. Genet. 42(1):45-52(2010)
- Styrkarsdottir, U., et al. Nat. Genet. 41(1):15-17(2009)
- Chan, M.W., et al. Neoplasia 10(9):908-919(2008)
- Tanabe, C., et al. Biochem. Biophys. Res. Commun. 352(1):111-117(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ADAM19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-236 amino acids from the Central region of human ADAM19.
NCBI Gene ID #:
8728
NCBI Official Name:
Disintegrin and metalloproteinase domain-containing protein 19
NCBI Official Symbol:
ADAM19
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
105 kDa
Protein Accession #:
Q9H013
Protein GI Number:
302393821
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
Q9H013
User NOte:
Optimal dilutions for each application to be determined by the researcher.