PRSS3 Antibody
Code | Size | Price |
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PSI-55-214-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Trypsin-3, Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, Trypsin IV, PRSS3, PRSS4, TRY3, TRY4
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Background:
PRSS3 encodes a trypsinogen, which is a member of the
trypsin family of serine proteases. This enzyme is expressed in the
brain and pancreas and is resistant to common trypsin inhibitors.
It is active on peptide linkages involving the carboxyl group of
lysine or arginine. PRSS3 is localized to the locus of T cell
receptor beta variable orphans on chromosome 9. Four transcript
variants encoding different isoforms have been described for this
gene.
Background References:
- Jiang, G., et al. Gut 59(11):1535-1544(2010)
- Nakanishi, J., et al. J. Invest. Dermatol. 130(4):944-952(2010)
- Salameh, M.A., et al. J. Biol. Chem. 285(3):1939-1949(2010)
- Rosendahl, J., et al. Pancreatology 10 (2-3), 243-249 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PRSS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human PRSS3.
NCBI Official Name:
Trypsin-3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P35030
Protein GI Number:
209572698
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
P35030-1
User NOte:
Optimal dilutions for each application to be determined by the researcher.