CCL27 Antibody
Code | Size | Price |
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PSI-58-929-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
C-C motif chemokine 27, CC chemokine ILC, Cutaneous T-cell-attracting chemokine, CTACK, ESkine, IL-11 R-alpha-locus chemokine, Skinkine, Small-inducible cytokine A27, CCL27, ILC, SCYA27
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is one of several CC cytokine genes clustered on
the p-arm of chromosome 9. Cytokines are a family of secreted
proteins involved in immunoregulatory and inflammatory processes.
The CC cytokines are proteins characterized by two adjacent
cysteines. The protein encoded by this gene is chemotactic for
skin-associated memory T lymphocytes. This cytokine may also play a
role in mediating homing of lymphocytes to cutaneous sites. It
specifically binds to chemokine receptor 10 (CCR10). Studies of a
similar murine protein indicate that these protein-receptor
interactions have a pivotal role in T cell-mediated skin
inflammation.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Siezen, C.L., et al. Pediatr. Infect. Dis. J. 28(4):333-335(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CCL27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the C-terminal region of human CCL27.
NCBI Gene ID #:
10850
NCBI Official Name:
C-C motif chemokine 27
NCBI Official Symbol:
CCL27
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
13 kDa
Protein Accession #:
Q9Y4X3
Protein GI Number:
7674366
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Immunology
Swissprot #:
Q9Y4X3
User NOte:
Optimal dilutions for each application to be determined by the researcher.