IL17D Antibody

ProSci
Product Code: PSI-57-908
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-908-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Further Information

Additional Names:
Interleukin-17D, IL-17D, Interleukin-27, IL-27, IL17D, IL27
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.
Background References:
  • Davila, S., et al. Genes Immun. 11(3):232-238(2010)
  • Fakruddin, J.M., et al. Blood 109(5):1841-1849(2007)
  • Larousserie, F., et al. J. Immunol. 176(10):5890-5897(2006)
  • Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This IL17D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-183 amino acids from the C-terminal region of human IL17D.
NCBI Gene ID #:
53342
NCBI Official Name:
Interleukin-17D
NCBI Official Symbol:
IL17D
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
Q8TAD2
Protein GI Number:
46576614
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Immunology
Swissprot #:
Q8TAD2
User NOte:
Optimal dilutions for each application to be determined by the researcher.