PF4 Antibody

ProSci
Product Code: PSI-61-201
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-201-200ul200ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:2000 dilution + human spleen lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:2000 dilution + human spleen lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Platelet factor 4, PF-4, C-X-C motif chemokine 4, Iroplact, Oncostatin-A, Platelet factor 4, short form, PF4, CXCL4, SCYB4
Application Note:
For WB starting dilution is: 1:2000
Background:
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
Background References:
  • Poncz M.,et al.Blood 69:219-223(1987).
  • Eisman R.,et al.Blood 76:336-344(1990).
  • Zhang C.,et al.Blood 98:610-617(2001).
  • Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PF4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from human PF4.
NCBI Gene ID #:
5196
NCBI Official Name:
Platelet factor 4
NCBI Official Symbol:
PF4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
11 kDa
Protein Accession #:
P02776
Protein GI Number:
130304
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Immunology
Swissprot #:
P02776
User NOte:
Optimal dilutions for each application to be determined by the researcher.