PLAUR Antibody
Code | Size | Price |
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PSI-61-036-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Urokinase plasminogen activator surface receptor, U-PAR, uPAR, Monocyte activation antigen Mo3, CD87, PLAUR, MO3, UPAR
Application Note:
For IHC-P starting dilution is: 1:25
Background:
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Background References:
- Roldan A.L.,et al.EMBO J. 9:467-474(1990).
- Min H.Y.,et al.J. Immunol. 148:3636-3642(1992).
- Bayraktutan U.,et al.Biochem. Soc. Trans. 21:395-395(1993).
- Pyke C.,et al.FEBS Lett. 326:69-74(1993).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PLAUR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 273-305 amino acids from the C-terminal region of human PLAUR.
NCBI Gene ID #:
5329
NCBI Official Name:
Urokinase plasminogen activator surface receptor
NCBI Official Symbol:
PLAUR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
Q03405
Protein GI Number:
465003
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Immunology
Swissprot #:
Q03405
User NOte:
Optimal dilutions for each application to be determined by the researcher.