CEACAM3 Antibody
| Code | Size | Price |
|---|
| PSI-57-311-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Carcinoembryonic antigen-related cell adhesion molecule 3, Carcinoembryonic antigen CGM1, CD66d, CEACAM3, CD66D, CGM1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the family of
carcinoembryonic antigen-related cell adhesion molecules (CEACAMs),
which are used by several bacterial pathogens to bind and invade
host cells. The encoded transmembrane protein directs phagocytosis
of several bacterial species that is dependent on the small GTPase
Rac. It is thought to serve an important role in controlling
human-specific pathogens by the innate immune system. Alternatively
spliced transcript variants have been described, but their
biological validity has not been determined.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Tsavaris, N., et al.Chemother 21(6):673-680(2009)
- Skubitz, K.M., et al.Transl Med 6, 78 (2008) :
- Stern-Ginossar, N., et al. J. Immunol. 179(7):4424-4434(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CEACAM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the C-terminal region of human CEACAM3.
NCBI Gene ID #:
1084
NCBI Official Name:
Carcinoembryonic antigen-related cell adhesion molecule 3
NCBI Official Symbol:
CEACAM3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
P40198
Protein GI Number:
218511974
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Immunology,
Swissprot #:
P40198
User NOte:
Optimal dilutions for each application to be determined by the researcher.