IL6 Antibody
| Code | Size | Price |
|---|
| PSI-56-451-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Interleukin-6, IL-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2, IL6, IFNB2
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a cytokine that functions in
inflammation and the maturation of B cells. The protein is
primarily produced at sites of acute and chronic inflammation,
where it is secreted into the serum and induces a transcriptional
inflammatory response through interleukin 6 receptor, alpha. The
functioning of this gene is implicated in a wide variety of
inflammation-associated disease states, including suspectibility to
diabetes mellitus and systemic juvenile rheumatoid arthritis.
Background References:
- Perez, A.B., et al. Hum. Immunol. 71(11):1135-1140(2010)
- Weng, X.M., et al. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 24(1):42-44(2010)
- Santhosh, S., et al. Trop Gastroenterol 31(1):30-33(2010)
- Gein, O.N., et al. Patol Fiziol Eksp Ter 1, 10-13 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This IL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the Central region of human IL6.
NCBI Gene ID #:
3569
NCBI Official Name:
Interleukin-6
NCBI Official Symbol:
IL6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
P05231
Protein GI Number:
124347
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Immunology,Obesity,Neuroscience,Signal Transduction
Swissprot #:
P05231
User NOte:
Optimal dilutions for each application to be determined by the researcher.