OPCML Antibody
| Code | Size | Price |
|---|
| PSI-60-633-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Opioid-binding protein/cell adhesion molecule, OBCAM, OPCML, Opioid-binding cell adhesion molecule, IgLON family member 1, OPCML, IGLON1, OBCAM
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the IgLON subfamily in the
immunoglobulin protein superfamily. The encoded protein is
localized in the plasma membrane and may have an accessory role in
opioid receptor function. This gene has an ortholog in rat and
bovine. The opioid binding-cell adhesion molecule encoded by the
rat gene binds opioid alkaloids in the presence of acidic lipids,
exhibits selectivity for mu ligands and acts as a GPI-anchored
protein. Since the encoded protein is highly conserved in species
during evolution, it may have a fundamental role in mammalian
systems. Two transcript variants encoding different isoforms have
been found for this gene.
Background References:
- Bailey, S.D., et al. Diabetes Care (2010) In press :
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Stolk, L., et al. Nat. Genet. (2009) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Immunogen:
This OPCML antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-200 amino acids from the Central region of human OPCML.
NCBI Gene ID #:
4978
NCBI Official Name:
Opioid-binding protein/cell adhesion molecule
NCBI Official Symbol:
OPCML
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
Q14982
Protein GI Number:
2497326
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience
Swissprot #:
Q14982
User NOte:
Optimal dilutions for each application to be determined by the researcher.