MSX2 Antibody

ProSci
Product Code: PSI-57-906
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-906-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

Further Information

Additional Names:
Homeobox protein MSX-2, Homeobox protein Hox-8, MSX2, HOX8
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
Background References:
  • Nikopensius, T., et al. Birth Defects Res. PartClin. Mol. Teratol. 88(9):748-756(2010)
  • Satoh, K., et al. J. Gastroenterol. 45(7):763-770(2010)
  • Doi, T., et al. J. Pediatr. Surg. 45(6):1187-1191(2010)
  • Jagomagi, T., et al. Eur. J. Oral Sci. 118(3):213-220(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Xenopus, Bovine, Mouse, Rat, Zebrafish
Immunogen:
This MSX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the Central region of human MSX2.
NCBI Gene ID #:
4488
NCBI Official Name:
Homeobox protein MSX-2
NCBI Official Symbol:
MSX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Protein Accession #:
P35548
Protein GI Number:
311033429
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience
Swissprot #:
P35548
User NOte:
Optimal dilutions for each application to be determined by the researcher.