GNAQ Antibody
| Code | Size | Price |
|---|
| PSI-57-538-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein alpha-q, GNAQ, GAQ
Application Note:
For WB starting dilution is: 1:1000
Background:
This locus encodes a guanine nucleotide-binding protein.
The encoded protein, an alpha subunit in the Gq class, couples a
seven-transmembrane domain receptor to activation of phospolipase
C-beta. Mutations at this locus have been associated with problems
in platelet activation and aggregation. A related pseudogene exists
on chromosome 2.
Background References:
- Dratviman-Storobinsky, O., et al. Invest. Ophthalmol. Vis. Sci. 51(12):6180-6182(2010)
- Crouthamel, M., et al. Mol. Pharmacol. 78(4):767-777(2010)
- Chillar, A., et al. Biochemistry 49(30):6365-6374(2010)
- Klenke, S., et al. Pharmacogenet. Genomics 20(8):476-484(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat, Xenopus
Immunogen:
This GNAQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-78 amino acids from the N-terminal region of human GNAQ.
NCBI Gene ID #:
2776
NCBI Official Name:
Guanine nucleotide-binding protein G(q) subunit alpha
NCBI Official Symbol:
GNAQ
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
P50148
Protein GI Number:
251757492
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience,Signal Transduction
Swissprot #:
P50148
User NOte:
Optimal dilutions for each application to be determined by the researcher.