PGR Antibody
| Code | Size | Price |
|---|
| PSI-60-739-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the steroid receptor
superfamily. The encoded protein mediates the physiological effects
of progesterone, which plays a central role in reproductive events
associated with the establishment and maintenance of pregnancy.
This gene uses two distinct promotors and translation start sites
in the first exon to produce two isoforms, A and B. The two
isoforms are identical except for the additional 165 amino acids
found in the N-terminus of isoform B and mediate their own response
genes and physiologic effects with little overlap. The location of
transcription initiation for isoform A has not been clearly
determined.
Background References:
- Geradts, J., et al. Cancer Invest. 28(9):969-977(2010)
- Tang, P., et al. Cancer Invest. 28(9):978-982(2010)
- Van Belle, V., et al. J. Clin. Oncol. 28(27):4129-4134(2010)
- Taylor, K.C., et al. Horm Res Paediatr (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Rat
Immunogen:
This PGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 833-861 amino acids from the C-terminal region of human PGR.
NCBI Gene ID #:
5241
NCBI Official Name:
Progesterone receptor
NCBI Official Symbol:
PGR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
99 kDa
Protein Accession #:
P06401
Protein GI Number:
90110048
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience,Signal Transduction
Swissprot #:
P06401
User NOte:
Optimal dilutions for each application to be determined by the researcher.