WNT8B Antibody

ProSci
Product Code: PSI-57-372
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-372-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution + K562 whole cell lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:1000 dilution + K562 whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Protein Wnt-8b, WNT8B
Application Note:
For WB starting dilution is: 1:1000
Background:
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.
Background References:
  • Katoh, M., et al. Int. J. Oncol. 30(5):1273-1277(2007)
  • Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
  • Deloukas, P., et al. Nature 429(6990):375-381(2004)
  • Saitoh, T., et al. Int. J. Oncol. 20(5):999-1003(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This WNT8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the C-terminal region of human WNT8B.
NCBI Gene ID #:
7479
NCBI Official Name:
Protein Wnt-8b
NCBI Official Symbol:
WNT8B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q93098
Protein GI Number:
66774217
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience,Signal Transduction
Swissprot #:
Q93098
User NOte:
Optimal dilutions for each application to be determined by the researcher.