SYT4 Antibody

ProSci
Product Code: PSI-60-490
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-490-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A2058 cell line lysates (35ug/lane).

Western blot analysis in A2058 cell line lysates (35ug/lane).

Further Information

Additional Names:
Synaptotagmin-4, Synaptotagmin IV, SytIV, SYT4, KIAA1342
Application Note:
For WB starting dilution is: 1:1000
Background:
SYT4 may be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
Background References:
  • Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)
  • Sonuga-Barke, E.J., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 147B (8), 1359-1368 (2008) :
  • Ferguson, G.D., et al. J. Biol. Chem. 275(47):36920-36926(2000)
  • Mizutani, A., et al. J. Biol. Chem. 275(13):9823-9831(2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SYT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-85 amino acids from the N-terminal region of human SYT4.
NCBI Gene ID #:
6860
NCBI Official Name:
Synaptotagmin-4
NCBI Official Symbol:
SYT4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
Q9H2B2
Protein GI Number:
18202937
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience,Signal Transduction
Swissprot #:
Q9H2B2
User NOte:
Optimal dilutions for each application to be determined by the researcher.