SYT1 Antibody
| Code | Size | Price |
|---|
| PSI-57-214-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Synaptotagmin-1, Synaptotagmin I, SytI, p65, SYT1, SVP65, SYT
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The synaptotagmins are integral membrane proteins of
synaptic vesicles thought to serve as Ca(2+) sensors in the process
of vesicular trafficking and exocytosis. Calcium binding to
synaptotagmin-1 participates in triggering neurotransmitter release
at the synapse (Fernandez-Chacon et al., 2001 [PubMed
11242035]).
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Musch, M.W., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 298 (2), G203-G211 (2010) :
- Kathir, K.M., et al. Biochim. Biophys. Acta 1798(2):297-302(2010)
- Pattaro, C., et al. BMC Med. Genet. 11, 41 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Monkey, Mouse, Rat
Immunogen:
This SYT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from the C-terminal region of human SYT1.
NCBI Gene ID #:
6857
NCBI Official Name:
Synaptotagmin-1
NCBI Official Symbol:
SYT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
P21579
Protein GI Number:
135086
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience,Signal Transduction
Swissprot #:
P21579
User NOte:
Optimal dilutions for each application to be determined by the researcher.