POMT1 Antibody
| Code | Size | Price |
|---|
| PSI-56-386-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein O-mannosyl-transferase 1, Dolichyl-phosphate-mannose--protein mannosyltransferase 1, POMT1
Application Note:
For IHC-P starting dilution is: 1:10~50
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
Background:
The protein encoded by this gene is an
O-mannosyltransferase that requires interaction with the product of
the POMT2 gene for enzymatic function. The encoded protein is found
in the membrane of the endoplasmic reticulum. Defects in this gene
are a cause of Walker-Warburg syndrome (WWS) and limb-girdle
muscular dystrophy type 2K (LGMD2K). Several transcript variants
encoding different isoforms have been found for this gene.
Background References:
- Manya, H., et al. J. Biochem. 147(3):337-344(2010)
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- Cotarelo, R.P., et al. Clin. Genet. 76(1):108-112(2009)
- Mercuri, E., et al. Neurology 72(21):1802-1809(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This POMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 706-735 amino acids from the C-terminal region of human POMT1.
NCBI Gene ID #:
10585
NCBI Official Name:
Protein O-mannosyl-transferase 1
NCBI Official Symbol:
POMT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
85 kDa
Protein Accession #:
Q9Y6A1
Protein GI Number:
332278226
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience,Signal Transduction
Swissprot #:
Q9Y6A1
User NOte:
Optimal dilutions for each application to be determined by the researcher.