CMGA Antibody
| Code | Size | Price |
|---|
| PSI-56-038-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Chromogranin-A, CgA, Pituitary secretory protein I, SP-I, Vasostatin-1, Vasostatin I, Vasostatin-2, Vasostatin II, EA-92, ES-43, Pancreastatin, SS-18, WA-8, WE-14, LF-19, AL-11, GV-19, GR-44, ER-37, CHGA
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a member of the
chromogranin/secretogranin family of neuroendocrine secretory
proteins. It is found in secretory vesicles of neurons and
endocrine cells. This gene product is a precursor to three
biologically active peptides; vasostatin, pancreastatin, and
parastatin. These peptides act as autocrine or paracrine negative
modulators of the neuroendocrine system. Other peptides, including
chromostatin, beta-granin, WE-14 and GE-25, are also derived from
the full-length protein. However, biological activities for these
molecules have not been shown.
Background References:
- Ezzi, S.A., et al. J. Neurochem. 115(5):1102-1111(2010)
- Ma, Z., et al. J. Urol. 184(3):1182-1188(2010)
- Ramella, R., et al. J. Cell. Biochem. 110(1):70-79(2010)
- Dag, E., et al. Peptides 31(5):932-937(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CMGA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-404 amino acids from the C-terminal region of human CMGA.
NCBI Gene ID #:
1113
NCBI Official Name:
Chromogranin-A
NCBI Official Symbol:
CHGA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
P10645
Protein GI Number:
215274270
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience,Signal Transduction
Swissprot #:
P10645
User NOte:
Optimal dilutions for each application to be determined by the researcher.