SSX4 Antibody
| Code | Size | Price |
|---|
| PSI-56-923-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein SSX4, Cancer/testis antigen 54, CT54, SSX4, SSX4A
Application Note:
For WB starting dilution is: 1:1000
Background:
The product of this gene belongs to the family of highly
homologous synovial sarcoma X (SSX) breakpoint proteins. These
proteins may function as transcriptional repressors. They are also
capable of eliciting spontaneously humoral and cellular immune
responses in cancer patients, and are potentially useful targets in
cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have
been involved in the t(X;18) translocation characteristically found
in all synovial sarcomas. This translocation results in the fusion
of the synovial sarcoma translocation gene on chromosome 18 to one
of the SSX genes on chromosome X. Chromosome Xp11 contains a
segmental duplication resulting in two identical copies of synovial
sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail
orientation. This gene, SSX4B, represents the more centromeric
copy. Two transcript variants encoding distinct isoforms have been
identified for this gene.
Background References:
- Ayyoub, M., et al. J. Immunol. 174(8):5092-5099(2005)
- Ross, M.T., et al. Nature 434(7031):325-337(2005)
- Gure, A.O., et al. Int. J. Cancer 101(5):448-453(2002)
- Brodin, B., et al. Gene 268 (1-2), 173-182 (2001) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SSX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the Central region of human SSX4.
NCBI Gene ID #:
548313, 6759
NCBI Official Name:
Protein SSX4
NCBI Official Symbol:
SSX4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
O60224
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity
Swissprot #:
O60224
User NOte:
Optimal dilutions for each application to be determined by the researcher.