EPAS1 Antibody
| Code | Size | Price |
|---|
| PSI-57-549-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Endothelial PAS domain-containing protein 1, EPAS-1, Basic-helix-loop-helix-PAS protein MOP2, Class E basic helix-loop-helix protein 73, bHLHe73, HIF-1-alpha-like factor, HLF, Hypoxia-inducible factor 2-alpha, HIF-2-alpha, HIF2-alpha, Member of PAS protein 2, PAS domain-containing protein 2, EPAS1, BHLHE73, HIF2A, MOP2, PASD2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a transcription factor involved in the
induction of genes regulated by oxygen, which is induced as oxygen
levels fall. The encoded protein contains a basic-helix-loop-helix
domain protein dimerization domain as well as a domain found in
proteins in signal transduction pathways which respond to oxygen
levels. Mutations in this gene are associated with erythrocytosis
familial type 4.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Yi, X., et al. Science 329(5987):75-78(2010)
- Bougatef, F., et al. PLoS ONE(8), E12265 (2010) :
- Hossein Ghaderian, S.M., et al. Pathology 42(5):446-453(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This EPAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 577-605 amino acids from the C-terminal region of human EPAS1.
NCBI Gene ID #:
2034
NCBI Official Name:
Endothelial PAS domain-containing protein 1
NCBI Official Symbol:
EPAS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
96 kDa
Protein Accession #:
Q99814
Protein GI Number:
32470617
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity
Swissprot #:
Q99814
User NOte:
Optimal dilutions for each application to be determined by the researcher.