OS9 Antibody
| Code | Size | Price |
|---|
| PSI-59-053-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein OS-9, Amplified in osteosarcoma 9, OS9
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that is highly expressed in
osteosarcomas. This protein binds to the hypoxia-inducible factor 1
(HIF-1), a key regulator of the hypoxic response and angiogenesis,
and promotes the degradation of one of its subunits. Alternate
transcriptional splice variants, encoding different isoforms, have
been characterized.
Background References:
- Feng, T., et al. Hum. Genet. 128(3):269-280(2010)
- Mikami, K., et al. Glycobiology 20(3):310-321(2010)
- Hosokawa, N., et al. J. Biol. Chem. 284(25):17061-17068(2009)
- Jansen, B.J., et al. Mol. Immunol. 46(4):505-515(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This OS9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the C-terminal region of human OS9.
NCBI Gene ID #:
10956
NCBI Official Name:
Protein OS-9
NCBI Official Symbol:
OS9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
76 kDa
Protein Accession #:
Q13438
Protein GI Number:
3024310
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity
Swissprot #:
Q13438
User NOte:
Optimal dilutions for each application to be determined by the researcher.