LONP1 Antibody
Code | Size | Price |
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PSI-60-602-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Lon protease homolog, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03120}, 3421- {ECO:0000255|HAMAP-Rule:MF_03120}, LONHs, Lon protease-like protein {ECO:0000255|HAMAP-Rule:MF_03120}, LONP {ECO:0000255|HAMAP-Rule:MF_03120}, Mitochondrial ATP-dependent protease Lon {ECO:0000255|HAMAP-Rule:MF_03120}, Serine protease 15 {ECO:0000255|HAMAP-Rule:MF_03120}, LONP1 {ECO:0000255|HAMAP-Rule:MF_03120}, PRSS15
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a mitochondrial matrix protein in the
Lon family of ATP-dependent proteases. A similar E. coli protein
regulates gene expression by targeting specific regulatory proteins
for degradation. This protein binds a specific sequence in the
light and heavy chain promoters of the mitochondrial genome which
are involved in regulation of DNA replication and transcription.
Background References:
- Hansen, J., et al. Neurobiology 153(2):474-482(2008)
- Chen, S.H., et al. Nucleic Acids Res. 36(4):1273-1287(2008)
- Bogenhagen, D.F., et al. J. Biol. Chem. 283(6):3665-3675(2008)
- Bayot, A., et al. Biochimie 90(2):260-269(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This LONP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-418 amino acids from the Central region of human LONP1.
NCBI Gene ID #:
9361
NCBI Official Name:
Lon protease homolog, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03120}
NCBI Official Symbol:
LONP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
106 kDa
Protein Accession #:
P36776
Protein GI Number:
12644239
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity
Swissprot #:
P36776
User NOte:
Optimal dilutions for each application to be determined by the researcher.