ADA Antibody
| Code | Size | Price |
|---|
| PSI-55-962-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Adenosine deaminase, Adenosine aminohydrolase, ADA, ADA1
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene encodes an enzyme that catalyzes the hydrolysis
of adenosine to inosine. Various mutations have been described for
this gene and have been linked to human diseases. Deficiency in
this enzyme causes a form of severe combined immunodeficiency
disease (SCID), in which there is dysfunction of both B and T
lymphocytes with impaired cellular immunity and decreased
production of immunoglobulins, whereas elevated levels of this
enzyme have been associated with congenital hemolytic anemia.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Gloria-Bottini, F., et al. Am. J. Med. Sci. 340(2):103-108(2010)
- Levine, A.J., et al. Cancer Epidemiol. Biomarkers Prev. 19(7):1812-1821(2010)
- Spina, C., et al. Cancer Invest. (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ADA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-314 amino acids from the C-terminal region of human ADA.
NCBI Gene ID #:
100
NCBI Official Name:
Adenosine deaminase
NCBI Official Symbol:
ADA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
P00813
Protein GI Number:
113339
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity
Swissprot #:
P00813
User NOte:
Optimal dilutions for each application to be determined by the researcher.