P2RX3 Antibody
| Code | Size | Price |
|---|
| PSI-60-165-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
P2X purinoceptor 3, P2X3, ATP receptor, Purinergic receptor, P2RX3
Application Note:
For WB starting dilution is: 1:1000
Background:
The product of this gene belongs to the family of
purinoceptors for ATP. This receptor functions as a ligand-gated
ion channel and may transduce ATP-evoked nociceptor activation.
Mouse studies suggest that this receptor is important for
peripheral pain responses, and also participates in pathways
controlling urinary bladder volume reflexes. It is possible that
the development of selective antagonists for this receptor may have
a therapeutic potential in pain relief and in the treatment of
disorders of urine storage.
Background References:
- Allsopp, R.C., et al. J. Biol. Chem. 285(43):32770-32777(2010)
- Beneng, K., et al. IntOral Maxillofac Surg 39(8):815-819(2010)
- Nair, A., et al. Cell. Mol. Neurobiol. 30(4):505-509(2010)
- Jacques-Silva, M.C., et al. Proc. Natl. Acad. Sci. U.S.A. 107(14):6465-6470(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This P2RX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 330-356 amino acids from the C-terminal region of human P2RX3.
NCBI Gene ID #:
5024
NCBI Official Name:
P2X purinoceptor 3
NCBI Official Symbol:
P2RX3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
P56373
Protein GI Number:
259016295
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Neuroscience
Swissprot #:
P56373
User NOte:
Optimal dilutions for each application to be determined by the researcher.