KCNA5 Antibody
| Code | Size | Price |
|---|
| PSI-58-900-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Potassium voltage-gated channel subfamily A member 5, HPCN1, Voltage-gated potassium channel HK2, Voltage-gated potassium channel subunit Kv15, KCNA5
Application Note:
For WB starting dilution is: 1:1000
Background:
Potassium channels represent the most complex class of
voltage-gated ino channels from both functional and structural
standpoints. Their diverse functions include regulating
neurotransmitter release, heart rate, insulin secretion, neuronal
excitability, epithelial electrolyte transport, smooth muscle
contraction, and cell volume. Four sequence-related potassium
channel genes - shaker, shaw, shab, and shal - have been identified
in Drosophila, and each has been shown to have human homolog(s).
This gene encodes a member of the potassium channel, voltage-gated,
shaker-related subfamily. This member contains six
membrane-spanning domains with a shaker-type repeat in the fourth
segment. It belongs to the delayed rectifier class, the function of
which could restore the resting membrane potential of beta cells
after depolarization and thereby contribute to the regulation of
insulin secretion. This gene is intronless, and the gene is
clustered with genes KCNA1 and KCNA6 on chromosome 12. [provided by
RefSeq].
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Wipff, J., et al. Arthritis Rheum. 62(10):3093-3100(2010)
- Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)
- Dou, Y., et al. Am. J. Physiol., Cell Physiol. 298 (6), C1343-C1352 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KCNA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-536 amino acids from the C-terminal region of human KCNA5.
NCBI Gene ID #:
3741
NCBI Official Name:
Potassium voltage-gated channel subfamily A member 5
NCBI Official Symbol:
KCNA5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
Protein Accession #:
P22460
Protein GI Number:
146345443
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Neuroscience
Swissprot #:
P22460
User NOte:
Optimal dilutions for each application to be determined by the researcher.