PSEN2 Antibody
| Code | Size | Price |
|---|
| PSI-61-056-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Presenilin-2, PS-2, 3423-, AD3LP, AD5, E5-1, STM-2, Presenilin-2 NTF subunit, Presenilin-2 CTF subunit, PSEN2, AD4, PS2, PSNL2, STM2
Application Note:
For FACS starting dilution is: 1:25
For WB starting dilution is: 1:1000
For WB starting dilution is: 1:1000
Background:
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.
Background References:
- Levy-Lahad E.,et al.Science 269:973-977(1995).
- Rogaev E.I.,et al.Nature 376:775-778(1995).
- Li J.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:12180-12184(1995).
- Levy-Lahad E.,et al.Genomics 34:198-204(1996).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PSEN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-65 amino acids from the N-terminal region of human PSEN2(Presenilin-2 NTF subunit).
NCBI Gene ID #:
5664
NCBI Official Name:
Presenilin-2
NCBI Official Symbol:
PSEN2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
P49810
Protein GI Number:
1709858
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Neuroscience
Swissprot #:
P49810
User NOte:
Optimal dilutions for each application to be determined by the researcher.