ARNT2 Antibody
| Code | Size | Price |
|---|
| PSI-58-559-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Aryl hydrocarbon receptor nuclear translocator 2, ARNT protein 2, Class E basic helix-loop-helix protein 1, bHLHe1, ARNT2, BHLHE1, KIAA0307
Application Note:
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Background:
This gene encodes a member of the
basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of
transcription factors. The encoded protein acts as a partner for
several sensor proteins of the bHLH-PAS family, forming
heterodimers with the sensor proteins that bind regulatory DNA
sequences in genes responsive to developmental and environmental
stimuli. Under hypoxic conditions, the encoded protein complexes
with hypoxia-inducible factor 1alpha in the nucleus and this
complex binds to hypoxia-responsive elements in enhancers and
promoters of oxygen-responsive genes. A highly similar protein in
mouse forms functional complexes with both aryl hydrocarbon
receptors and Single-minded proteins, suggesting addition roles for
the encoded protein in the metabolism of xenobiotic compounds and
the regulation of neurogenesis, respectively.
Background References:
- Ramirez, J.M., et al. Eur. J. Immunol. 40(9):2450-2459(2010)
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- Chakrabarti, B., et al. Autism Res 2(3):157-177(2009)
- Ferreira, M.A., et al. Nat. Genet. 40(9):1056-1058(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This ARNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-278 amino acids from the Central region of human ARNT2.
NCBI Gene ID #:
9915
NCBI Official Name:
Aryl hydrocarbon receptor nuclear translocator 2
NCBI Official Symbol:
ARNT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Protein Accession #:
Q9HBZ2
Protein GI Number:
125987793
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Neuroscience
Swissprot #:
Q9HBZ2
User NOte:
Optimal dilutions for each application to be determined by the researcher.