MGLL Antibody

ProSci
Product Code: PSI-58-776
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-776-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 1
Western blot analysis in A2058 cell line lysates (35ug/lane).

Western blot analysis in A2058 cell line lysates (35ug/lane).

Further Information

Additional Names:
Monoglyceride lipase, MGL, HU-K5, Lysophospholipase homolog, Lysophospholipase-like, Monoacylglycerol lipase, MAGL, MGLL
Application Note:
For WB starting dilution is: 1:1000
Background:
Monoglyceride lipase (MGLL; EC 3.1.1.23) functions together with hormone-sensitive lipase (LIPE; MIM 151750) to hydrolyze intracellular triglyceride stores in adipocytes and other cells to fatty acids and glycerol. MGLL may also complement lipoprotein lipase (LPL; MIM 238600) in completing hydrolysis of monoglycerides resulting from degradation of lipoprotein triglycerides (Karlsson et al., 2001 [PubMed 11470505]).[supplied by OMIM].
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Karageorgos, I., et al. Mol Biosyst 6(8):1381-1388(2010)
  • Bertrand, T., et al. J. Mol. Biol. 396(3):663-673(2010)
  • Labar, G., et al. Chembiochem 11(2):218-227(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MGLL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-63 amino acids from the N-terminal region of human MGLL.
NCBI Gene ID #:
11343
NCBI Official Name:
Monoglyceride lipase
NCBI Official Symbol:
MGLL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
Q99685
Protein GI Number:
47117287
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Neuroscience,Signal Transduction
Swissprot #:
Q99685
User NOte:
Optimal dilutions for each application to be determined by the researcher.