SCNN1B Antibody
| Code | Size | Price |
|---|
| PSI-60-822-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Amiloride-sensitive sodium channel subunit beta, Beta-NaCH, Epithelial Na(+) channel subunit beta, Beta-ENaC, ENaCB, Nonvoltage-gated sodium channel 1 subunit beta, SCNEB, SCNN1B
Application Note:
For WB starting dilution is: 1:1000
Background:
Nonvoltage-gated, amiloride-sensitive, sodium channels
control fluid and electrolyte transport across epithelia in many
organs. These channels are heteromeric complexes consisting of 3
subunits: alpha, beta, and gamma. This gene encodes the beta
subunit, and mutations in this gene have been associated with
pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Song, W., et al. J. Biol. Chem. 285(13):9716-9728(2010)
- Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
- McGeachie, M., et al. Circulation 120(24):2448-2454(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SCNN1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-332 amino acids from the Central region of human SCNN1B.
NCBI Gene ID #:
6338
NCBI Official Name:
Amiloride-sensitive sodium channel subunit beta
NCBI Official Symbol:
SCNN1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
73 kDa
Protein Accession #:
P51168
Protein GI Number:
8928561
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Neuroscience,Signal Transduction
Swissprot #:
P51168
User NOte:
Optimal dilutions for each application to be determined by the researcher.