HSD17B1 Antibody

ProSci
Product Code: PSI-58-560
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-560-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

Further Information

Additional Names:
Estradiol 17-beta-dehydrogenase 1, 17-beta-hydroxysteroid dehydrogenase type 1, 17-beta-HSD 1, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, E2DH, Placental 17-beta-hydroxysteroid dehydrogenase, HSD17B1, E17KSR, EDH17B1, EDH17B2, EDHB17
Application Note:
For WB starting dilution is: 1:1000
Background:
Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.
Background References:
  • Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)
  • Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
  • Lamp, M., et al. Gynecol. Endocrinol. (2010) In press :
  • Haller, F., et al. J. Mol. Biol. 399(2):255-267(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HSD17B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-256 amino acids from the C-terminal region of human HSD17B1.
NCBI Gene ID #:
3292
NCBI Official Name:
Estradiol 17-beta-dehydrogenase 1
NCBI Official Symbol:
HSD17B1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
P14061
Protein GI Number:
313104233
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Neuroscience,Signal Transduction
Swissprot #:
P14061
User NOte:
Optimal dilutions for each application to be determined by the researcher.