ESR2 Antibody
| Code | Size | Price |
|---|
| PSI-60-629-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2, ESR2, ESTRB, NR3A2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the family of estrogen
receptors and superfamily of nuclear receptor transcription
factors. The gene product contains an N-terminal DNA binding domain
and C-terminal ligand binding domain and is localized to the
nucleus, cytoplasm, and mitochondria. Upon binding to
17beta-estradiol or related ligands, the encoded protein forms
homo- or hetero-dimers that interact with specific DNA sequences to
activate transcription. Some isoforms dominantly inhibit the
activity of other estrogen receptor family members. Several
alternatively spliced transcript variants of this gene have been
described, but the full-length nature of some of these variants has
not been fully characterized.
Background References:
- Fang, Y.J., et al. Tumour Biol. 31(6):651-658(2010)
- Hayes, D.F., et al. Clin. Pharmacol. Ther. 88(5):626-629(2010)
- Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
- Wurster, M., et al. Oncol. Rep. 24(3):653-659(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ESR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-527 amino acids from the C-terminal region of human ESR2.
NCBI Gene ID #:
2100
NCBI Official Name:
Estrogen receptor beta
NCBI Official Symbol:
ESR2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
Q92731
Protein GI Number:
6166154
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Neuroscience,Signal Transduction
Swissprot #:
Q92731
User NOte:
Optimal dilutions for each application to be determined by the researcher.