SYT5 Antibody

ProSci
Product Code: PSI-57-456
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-456-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).

Western blot analysis in K562 cell line lysates (35ug/lane).

Further Information

Additional Names:
Synaptotagmin-5, Synaptotagmin V, SytV, SYT5
Application Note:
For WB starting dilution is: 1:1000
Background:
SYT5 may be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface (By similarity).
Background References:
  • Martins-de-Souza, D., et al.Psychiatr Res (2010) In press :
  • Sreenath, A.S., et al. Clin. Biochem. 38(5):436-443(2005)
  • Mizutani, A., et al. J. Biol. Chem. 275(13):9823-9831(2000)
  • Craxton, M., et al. FEBS Lett. 460(3):417-422(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SYT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the Central region of human SYT5.
NCBI Gene ID #:
6861
NCBI Official Name:
Synaptotagmin-5
NCBI Official Symbol:
SYT5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
O00445
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Neuroscience,Signal Transduction
Swissprot #:
O00445
User NOte:
Optimal dilutions for each application to be determined by the researcher.