SNAP25 Antibody
| Code | Size | Price |
|---|
| PSI-59-662-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Synaptosomal-associated protein 25, SNAP-25, Super protein, SUP, Synaptosomal-associated 25 kDa protein, SNAP25, SNAP
Application Note:
For WB starting dilution is: 1:1000
Background:
Synaptic vesicle membrane docking and fusion is mediated
by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment
protein receptors) located on the vesicle membrane (v-SNAREs) and
the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE
complex consists of a bundle of four helices, one of which is
supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on
the plasma membrane, the protein syntaxin supplies one helix and
the protein encoded by this gene contributes the other two.
Therefore, this gene product is a presynaptic plasma membrane
protein involved in the regulation of neurotransmitter release. Two
alternative transcript variants encoding different protein isoforms
have been described for this gene.
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Greaves, J., et al. J. Biol. Chem. 285(32):24629-24638(2010)
- Oner, O., et al.Atten Disord (2010) In press :
- Zhang, H., et al. Eur. J. Paediatr. Neurol. (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Zebrafish, Bovine, Chicken, Mouse, Rat
Immunogen:
This SNAP25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the Central region of human SNAP25.
NCBI Gene ID #:
6616
NCBI Official Name:
Synaptosomal-associated protein 25
NCBI Official Symbol:
SNAP25
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
P60880
Protein GI Number:
46397726
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Neuroscience,Signal Transduction
Swissprot #:
P60880
User NOte:
Optimal dilutions for each application to be determined by the researcher.