Jagged 2 Antibody
Code | Size | Price |
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PSI-62-140-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Protein jagged-2, Jagged2, hJ2, JAG2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several ligands that activate Notch and related receptors.
Background References:
- Hayashi, T., et al., J. Androl. 22(6):999-1011 (2001).
- Lindner, V., et al., Am. J. Pathol. 159(3):875-883 (2001).
- Cereseto, A., et al., J. Cell. Physiol. 185(3):425-431 (2000).
- Tsai, S., et al., Blood 96(3):950-957 (2000).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Jagged 2 (JAG2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1209-1238 amino acids from the C-terminal region of human Jagged 2 (JAG2).
NCBI Gene ID #:
3714
NCBI Official Name:
Protein jagged-2
NCBI Official Symbol:
JAG2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
133 kDa
Protein Accession #:
Q9Y219
Protein GI Number:
116242598
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Obesity,Neuroscience,Signal Transduction
Swissprot #:
Q9Y219
User NOte:
Optimal dilutions for each application to be determined by the researcher.