SCD5 Antibody
| Code | Size | Price |
|---|
| PSI-56-815-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Stearoyl-CoA desaturase 5, Acyl-CoA-desaturase 4, HSCD5, Stearoyl-CoA 9-desaturase, SCD5, ACOD4, SCD4
Application Note:
For WB starting dilution is: 1:1000
Background:
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral
membrane protein of the endoplasmic reticulum that catalyzes the
formation of monounsaturated fatty acids from saturated fatty
acids. SCD may be a key regulator of energy metabolism with a role
in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4,
have been identified in mouse. In contrast, only 2 SCD isoforms,
SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1
shares about 85% amino acid identity with all 4 mouse SCD isoforms,
as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited
homology with the rodent SCDs and appears to be unique to primates
(Wang et al., 2005 [PubMed 15907797]).
Background References:
- Bailey, S.D., et al. Diabetes Care (2010) In press :
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This SCD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of human SCD5.
NCBI Gene ID #:
79966
NCBI Official Name:
Stearoyl-CoA desaturase 5
NCBI Official Symbol:
SCD5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
Q86SK9
Protein GI Number:
162416247
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
Q86SK9
User NOte:
Optimal dilutions for each application to be determined by the researcher.