SRC1 Antibody
Code | Size | Price |
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PSI-56-307-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Nuclear receptor coactivator 1, NCoA-1, Class E basic helix-loop-helix protein 74, bHLHe74, Protein Hin-2, RIP160, Renal carcinoma antigen NY-REN-52, Steroid receptor coactivator 1, SRC-1, NCOA1, BHLHE74, SRC1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene acts as a transcriptional
coactivator for steroid and nuclear hormone receptors. It is a
member of the p160/steroid receptor coactivator (SRC) family and
like other family members has histone acetyltransferase activity
and contains a nuclear localization signal, as well as bHLH and PAS
domains. The product of this gene binds nuclear receptors directly
and stimulates the transcriptional activities in a
hormone-dependent fashion. Alternatively spliced transcript
variants encoding different isoforms have been identified.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Son, Y.L., et al. FEBS Lett. 584(18):3862-3866(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- McIlroy, M., et al. Cancer Res. 70(4):1585-1594(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 594-625 amino acids from the Central region of human SRC1.
NCBI Gene ID #:
8648
NCBI Official Name:
Nuclear receptor coactivator 1
NCBI Official Symbol:
NCOA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
157 kDa
Protein Accession #:
Q15788
Protein GI Number:
158518533
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
Q15788
User NOte:
Optimal dilutions for each application to be determined by the researcher.