GC Antibody
| Code | Size | Price |
|---|
| PSI-61-272-200ul | 200ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Vitamin D-binding protein, DBP, VDB, Gc-globulin, Group-specific component, GC
Application Note:
For WB starting dilution is: 1:2000
Background:
Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
Background References:
- Cooke N.E.,et al.J. Clin. Invest. 76:2420-2424(1985).
- Yang F.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:7994-7998(1985).
- Braun A.,et al.Biochim. Biophys. Acta 1216:385-394(1993).
- Witke W.F.,et al.Genomics 16:751-754(1993).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 442-473 amino acids from human GC.
NCBI Gene ID #:
2638
NCBI Official Name:
Vitamin D-binding protein
NCBI Official Symbol:
GC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
P02774
Protein GI Number:
139641
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P02774
User NOte:
Optimal dilutions for each application to be determined by the researcher.