CPT1A Antibody
| Code | Size | Price |
|---|
| PSI-57-900-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Carnitine O-palmitoyltransferase 1, liver isoform, CPT1-L, Carnitine O-palmitoyltransferase I, liver isoform, CPT I, CPTI-L, Carnitine palmitoyltransferase 1A, CPT1A, CPT1
Application Note:
For WB starting dilution is: 1:1000
Background:
The mitochondrial oxidation of long-chain fatty acids is
initiated by the sequential action of carnitine
palmitoyltransferase I (which is located in the outer membrane and
is detergent-labile) and carnitine palmitoyltransferase II (which
is located in the inner membrane and is detergent-stable), together
with a carnitine-acylcarnitine translocase. CPT I is the key enzyme
in the carnitine-dependent transport across the mitochondrial inner
membrane and its deficiency results in a decreased rate of fatty
acid beta-oxidation. Alternatively spliced transcript variants
encoding different isoforms have been found for this gene.
Background References:
- Gessner, B.D., et al. Pediatrics 126(5):945-951(2010)
- Collins, S.A., et al. Mol. Genet. Metab. 101 (2-3), 200-204 (2010) :
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Song, S., et al. Mol. Cell. Endocrinol. 325 (1-2), 54-63 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CPT1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 728-756 amino acids from the C-terminal region of human CPT1A.
NCBI Gene ID #:
1374
NCBI Official Name:
Carnitine O-palmitoyltransferase 1, liver isoform
NCBI Official Symbol:
CPT1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
Protein Accession #:
P50416
Protein GI Number:
56405343
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P50416
User NOte:
Optimal dilutions for each application to be determined by the researcher.