SULF2 Antibody
| Code | Size | Price |
|---|
| PSI-56-647-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Extracellular sulfatase Sulf-2, hSulf-2, 316-, SULF2, KIAA1247
Application Note:
For WB starting dilution is: 1:1000
Background:
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).
Background References:
- Lai, J.P., et al. Hepatology 52(5):1680-1689(2010) Ellinor, P.T., et al. Nat. Genet. 42(3):240-244(2010) Lemjabbar-Alaoui, H., et al. Oncogene 29(5):635-646(2010) Tang, R., et al. J. Biol. Chem. 284(32):21505-21514(2009) Chau, B.N., et al. Cancer Res. 69(4):1368-1374(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This SULF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 824-852 amino acids from the C-terminal region of human SULF2.
NCBI Gene ID #:
55959
NCBI Official Name:
Extracellular sulfatase Sulf-2
NCBI Official Symbol:
SULF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
100 kDa
Protein Accession #:
Q8IWU5
Protein GI Number:
33112446
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
Q8IWU5
User NOte:
Optimal dilutions for each application to be determined by the researcher.