PPP1CB Antibody
| Code | Size | Price |
|---|
| PSI-57-323-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Serine/threonine-protein phosphatase PP1-beta catalytic subunit, PP-1B, PPP1CD, PPP1CB
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is one of the three
catalytic subunits of protein phosphatase 1 (PP1). PP1 is a
serine/threonine specific protein phosphatase known to be involved
in the regulation of a variety of cellular processes, such as cell
division, glycogen metabolism, muscle contractility, protein
synthesis, and HIV-1 viral transcription. Mouse studies suggest
that PP1 functions as a suppressor of learning and memory. Two
alternatively spliced transcript variants encoding distinct
isoforms have been observed.
Background References:
- Lee, J.H., et al. J. Biol. Chem. 285(32):24466-24476(2010)
- Fujiki, R., et al. Nature 459(7245):455-459(2009)
- Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009)
- Sueyoshi, T., et al. Mol. Pharmacol. 73(4):1113-1121(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Pig, Rabbit, Rat, Xenopus
Immunogen:
This PPP1CB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-327 amino acids from the C-terminal region of human PPP1CB.
NCBI Gene ID #:
5500
NCBI Official Name:
Serine/threonine-protein phosphatase PP1-beta catalytic subunit
NCBI Official Symbol:
PPP1CB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
P62140
Protein GI Number:
49065814
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P62140
User NOte:
Optimal dilutions for each application to be determined by the researcher.