NDUFS6 Antibody
| Code | Size | Price |
|---|
| PSI-60-731-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial, Complex I-13kD-A, CI-13kD-A, NADH-ubiquinone oxidoreductase 13 kDa-A subunit, NDUFS6
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a subunit of the NADH:ubiquinone
oxidoreductase (complex I), which is the first enzyme complex in
the electron transport chain of mitochondria. This complex
functions in the transfer of electrons from NADH to the respiratory
chain. The subunit encoded by this gene is one of seven subunits in
the iron-sulfur protein fraction. Mutations in this gene cause
mitochondrial complex I deficiency, a disease that causes a wide
variety of clinical disorders, including neonatal disease and
adult-onset neurodegenerative disorders.
Background References:
- Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)
- Martins-de-Souza, D., et al.Neural Transm 116(3):275-289(2009)
- Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)
- Starr, J.M., et al. Mech. Ageing Dev. 129(12):745-751(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This NDUFS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the Central region of human NDUFS6.
NCBI Gene ID #:
4726
NCBI Official Name:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
NCBI Official Symbol:
NDUFS6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
14 kDa
Protein Accession #:
O75380
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
O75380
User NOte:
Optimal dilutions for each application to be determined by the researcher.