STAR Antibody
| Code | Size | Price |
|---|
| PSI-58-562-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Steroidogenic acute regulatory protein, mitochondrial, StAR, START domain-containing protein 1, StARD1, STAR, STARD1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene plays a key role in the
acute regulation of steroid hormone synthesis by enhancing the
conversion of cholesterol into pregnenolone. This protein permits
the cleavage of cholesterol into pregnenolone by mediating the
transport of cholesterol from the outer mitochondrial membrane to
the inner mitochondrial membrane. Mutations in this gene are a
cause of congenital lipoid adrenal hyperplasia (CLAH), also called
lipoid CAH. A pseudogene of this gene is located on chromosome 13.
Background References:
- Shi, F.T., et al. J. Clin. Endocrinol. Metab. 95 (10), E172-E180 (2010) :
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Mizutani, T., et al. J. Biol. Chem. 285(36):28240-28251(2010)
- Sahakitrungruang, T., et al. J. Clin. Endocrinol. Metab. 95(7):3352-3359(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This STAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human STAR.
NCBI Gene ID #:
6770
NCBI Official Name:
Steroidogenic acute regulatory protein, mitochondrial
NCBI Official Symbol:
STAR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
P49675
Protein GI Number:
71152974
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P49675
User NOte:
Optimal dilutions for each application to be determined by the researcher.