MVP Antibody

ProSci
Product Code: PSI-63-443
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-443-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of MVK using rabbit polyclonal MVK Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MVK gene (Lane 2).

Western blot analysis of MVK using rabbit polyclonal MVK Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MVK gene (Lane 2).

Further Information

Additional Names:
Mevalonate kinase, MK, MVK
Application Note:
For WB starting dilution is: 1:1000
Background:
MVK encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of MVK results in mevalonic aciduria.
Background References:
  • Stojanov, S., et al., Arthritis Rheum. 50(6):1951-1958 (2004).
  • Nair, A.K., et al., J. Biol. Chem. 279(15):14937-14944 (2004).
  • Simon, A., et al., Neurology 62(6):994-997 (2004).
  • Houten, S.M., et al., J. Biol. Chem. 278(8):5736-5743 (2003).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MVK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-47 amino acids from the N-terminal region of human MVK.
NCBI Gene ID #:
4598
NCBI Official Name:
Mevalonate kinase
NCBI Official Symbol:
MVK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
Q03426
Protein GI Number:
417215
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
Q03426
User NOte:
Optimal dilutions for each application to be determined by the researcher.