BDHA1 Antibody
| Code | Size | Price |
|---|
| PSI-61-972-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial, PDHE1-A type I, PDHA1, PHE1A
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
The pyruvate dehydrogenase (PDH) complex is a
nuclear-encoded mitochondrial multienzyme complex that catalyzes
the overall conversion of pyruvate to acetyl-CoA and CO(2), and
provides the primary link between glycolysis and the tricarboxylic
acid (TCA) cycle. The PDH complex is composed of multiple copies of
three enzymatic components: pyruvate dehydrogenase (E1),
dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase
(E3). The E1 enzyme is a heterotetramer of two alpha and two beta
subunits. This gene encodes the E1 alpha 1 subunit containing the
E1 active site, and plays a key role in the function of the PDH
complex.
Background References:
- Glushakova, L.G., et al. Mol. Genet. Metab. 98(3):289-299(2009)
- Joao Silva, M., et al. Eur. J. Pediatr. 168(1):17-22(2009)
- Boichard, A., et al. Mol. Genet. Metab. 93(3):323-330(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Pig, Rat
Immunogen:
This BDHA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-255 amino acids from the Central region of human BDHA1.
NCBI Gene ID #:
5160
NCBI Official Name:
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
NCBI Official Symbol:
PDHA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
P08559
Protein GI Number:
129063
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P08559
User NOte:
Optimal dilutions for each application to be determined by the researcher.