CYP4A11 Antibody

ProSci
Product Code: PSI-63-267
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-267-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of anti-CYP4A11 (4A22) Antibody in NCI-H460 cell line lysates (35ug/lane).
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Confocal immunofluorescent analysis of CYP4A11 (4A22) Antibody with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).

Western blot analysis of anti-CYP4A11 (4A22) Antibody in NCI-H460 cell line lysates (35ug/lane).
Confocal immunofluorescent analysis of CYP4A11 (4A22) Antibody with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).

Further Information

Additional Names:
Cytochrome P450 4A11, 20-hydroxyeicosatetraenoic acid synthase, 20-HETE synthase, CYP4AII, CYPIVA11, Cytochrome P-450HK-omega, Cytochrome P450HL-omega, Fatty acid omega-hydroxylase, Lauric acid omega-hydroxylase, CYP4A11, CYP4A2
Application Note:
For WB starting dilution is: 1:1000

For IF starting dilution is: 1:10~50
Background:
CYP4A11 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate.
Background References:
  • Sugimoto,K., Hypertension 52 (6), 1142-1148 (2008)
  • Ward,N.C., Hypertension 51 (5), 1393-1398 (2008)
  • Nelson,D.R., Pharmacogenetics 14 (1), 1-18 (2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CYP4A11 (4A22) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-435 amino acids from the C-terminal region of human CYP4A11 (4A22).
NCBI Gene ID #:
1579
NCBI Official Name:
Cytochrome P450 4A11
NCBI Official Symbol:
CYP4A11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
Q02928
Protein GI Number:
2493371
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
Q02928
User NOte:
Optimal dilutions for each application to be determined by the researcher.