HSD17B4 Antibody
| Code | Size | Price |
|---|
| PSI-56-474-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Peroxisomal multifunctional enzyme type 2, MFE-2, 17-beta-hydroxysteroid dehydrogenase 4, 17-beta-HSD 4, D-bifunctional protein, DBP, Multifunctional protein 2, MPF-2, (3R)-hydroxyacyl-CoA dehydrogenase, 111n12, Enoyl-CoA hydratase 2, 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase, HSD17B4, EDH17B4
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a bifunctional enzyme
that is involved in the peroxisomal beta-oxidation pathway for
fatty acids. It also acts as a catalyst for the formation of
3-ketoacyl-CoA intermediates from both straight-chain and
2-methyl-branched-chain fatty acids. Defects in this gene that
affect the peroxisomal fatty acid beta-oxidation activity are a
cause of D-bifunctional protein deficiency (DBPD). An apparent
pseudogene of this gene is present on chromosome 8. [provided by
RefSeq].
Background References:
- Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Kashiwayama, Y., et al. J. Biol. Chem. 285(34):26315-26325(2010)
- Pierce, S.B., et al. Am. J. Hum. Genet. 87(2):282-288(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HSD17B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the Central region of human HSD17B4.
NCBI Gene ID #:
3295
NCBI Official Name:
Peroxisomal multifunctional enzyme type 2
NCBI Official Symbol:
HSD17B4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
80 kDa
Protein Accession #:
P51659
Protein GI Number:
1706396
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P51659
User NOte:
Optimal dilutions for each application to be determined by the researcher.