MTTP Antibody

ProSci
Product Code: PSI-63-765
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-765-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 2
Western blot analysis of MTTP Antibody in Hela(lane 1), 293(lane 2) cell line lysates (35ug/lane)
2 / 2
Formalin-fixed and paraffin-embedded human hepatocarcinoma with MTTP Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Western blot analysis of MTTP Antibody in Hela(lane 1), 293(lane 2) cell line lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human hepatocarcinoma with MTTP Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Further Information

Additional Names:
Microsomal triglyceride transfer protein large subunit, MTTP, MTP
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
MTTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a entral role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.
Background References:
  • Dai,K., et.al., Arterioscler. Thromb. Vasc. Biol. 30 (3), 568-574 (2010)
  • Oliveira,C.P., et.al., J. Gastroenterol. Hepatol. 25 (2), 357-361 (2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MTTP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 816-842 amino acids from the C-terminal region of human MTTP.
NCBI Gene ID #:
4547
NCBI Official Name:
Microsomal triglyceride transfer protein large subunit
NCBI Official Symbol:
MTTP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
99 kDa
Protein Accession #:
P55157
Protein GI Number:
1709167
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P55157
User NOte:
Optimal dilutions for each application to be determined by the researcher.