COX6B1 Antibody
| Code | Size | Price |
|---|
| PSI-56-356-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cytochrome c oxidase subunit 6B1, Cytochrome c oxidase subunit VIb isoform 1, COX VIb-1, COX6B1, COX6B
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Cytochrome c oxidase (COX), the terminal enzyme of the
mitochondrial respiratory chain, catalyzes the electron transfer
from reduced cytochrome c to oxygen. It is a heteromeric complex
consisting of 3 catalytic subunits encoded by mitochondrial genes
and multiple structural subunits encoded by nuclear genes. The
mitochondrially-encoded subunits function in electron transfer, and
the nuclear-encoded subunits may be involved in the regulation and
assembly of the complex. This nuclear gene encodes subunit VIb.
Mutations in this gene are associated with severe infantile
encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and
COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2,
respectively.
Background References:
- Lazarou, M., et al. FEBS J. 276(22):6701-6713(2009)
- Massa, V., et al. Am. J. Hum. Genet. 82(6):1281-1289(2008)
- Sirchia, R., et al. Biol. Chem. 388(5):457-465(2007)
- Schmidt, T.R., et al. Gene 286(1):13-19(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This COX6B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the C-terminal region of human COX6B1.
NCBI Gene ID #:
1340
NCBI Official Name:
Cytochrome c oxidase subunit 6B1
NCBI Official Symbol:
COX6B1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
10 kDa
Protein Accession #:
P14854
Protein GI Number:
117115
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P14854
User NOte:
Optimal dilutions for each application to be determined by the researcher.