GK Antibody
| Code | Size | Price |
|---|
| PSI-56-739-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Glycerol kinase, GK, Glycerokinase, ATP:glycerol 3-phosphotransferase, GK
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The product of this gene belongs to the FGGY kinase family
of proteins and encodes glycerol kinase. Glycerol kinase is a key
enzyme in the regulation of glycerol uptake and metabolism. It
catalyzes the phosphorylation of glycerol by ATP, yielding ADP and
glycerol-3-phosphate. Defects in this gene are the cause of
glycerol kinase deficiency (GKD). Alternatively spliced transcript
variants encoding different isoforms have been identified.
Background References:
- Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)
- Zhang, Y.H., et al. Pediatr. Res. 59 (4 PT 1), 590-592 (2006) :
- Ohira, R.H., et al. Biochem. Biophys. Res. Commun. 331(1):239-246(2005)
- Stepanian, S.V., et al. Mol. Genet. Metab. 80(4):412-418(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This GK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-51 amino acids from the N-terminal region of human GK.
NCBI Gene ID #:
2710
NCBI Official Name:
Glycerol kinase
NCBI Official Symbol:
GK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
P32189
Protein GI Number:
205830913
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P32189
User NOte:
Optimal dilutions for each application to be determined by the researcher.