ABCC11 Antibody
| Code | Size | Price |
|---|
| PSI-61-664-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
ATP-binding cassette sub-family C member 11, Multidrug resistance-associated protein 8, ABCC11, MRP8
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
ABCC11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1.
Background References:
- Martin, A., et al. J. Invest. Dermatol. 130(2):529-540(2010)
- J. Hum. Genet. 54(9):499-503(2009)
- Sato, T., et al. J. Hum. Genet. 54(7):409-413(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ABCC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 amino acids from the N-terminal region of human ABCC11.
NCBI Gene ID #:
85320
NCBI Official Name:
ATP-binding cassette sub-family C member 11
NCBI Official Symbol:
ABCC11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
154 kDa
Protein Accession #:
Q96J66
Protein GI Number:
74762666
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
Q96J66
User NOte:
Optimal dilutions for each application to be determined by the researcher.